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In view of its profound impact on therapy and survival, we developed and validated a score to identify the presence of SCLC early in the course of LEMS. Lambert-Eaton myasthenic syndrome (LEMS) is an autoimmune disease that targets the P/Q-type voltage-gated calcium channel (VGCC) at the motor neuron terminal of the neuromuscular junction. Knowledge of subtle clinical features and laboratory abnormalities that accompany LEMS permits the early identification of the disorder. new·what·how·langs·contacts·what·how·langs·contactsWe need her photosAlbum: venomous_dolly [178 files :: 413. Lambert-Eaton myasthenic syndrome (LEMS) is an uncommon disorder of neuromuscular junction transmission with the primary clinical manifestation of muscle weakness. 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